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2019-12-09
 Laboratorij za farmakogenetiko

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PUBLIKACIJE / PUBLICATIONS

Pubmed

COBISS

ČLANKI / RESEARCH PAPERS 2019

REDENŠEK, Sara, FLISAR, Dušan, KOJOVIĆ, Maja, GREGORIČ KRAMBERGER, Milica, GEORGIEV, Dejan, PIRTOŠEK, Zvezdan, TROŠT, Maja, DOLŽAN, Vita. Dopaminergic pathway genes influence adverse events related to dopaminergic treatment in Parkinson's disease. Frontiers in pharmacology, 2019, vol. 10, 1-10, doi: 10.3389/fphar.2019.00008. [COBISS.SI-ID 34173401]

ŠOŠTARIČ, Anja, JENKO BIZJAN, Barbara, ROTOVNIK-KOZJEK, Nada, OVIJAČ, Darja, ŠUPUT, Dušan, MILISAV, Irina, DOLŽAN, Vita. Detection of metabolic syndrome burden in healthy young adults may enable timely introduction of disease prevention. Archives of medical science, 2019, vol. 15, 1184-1194, doi: 10.5114/aoms.2019.87462. [COBISS.SI-ID 5696619]

ŠTRBAC, Danijela, GORIČAR, Katja, DOLŽAN, Vita, KOVAČ, Viljem. Evaluation of matrix metalloproteinase 9 serum concentration as a biomarker in malignant mesothelioma. Disease markers, 2019, 1-8, doi: 10.1155/2019/1242964. [COBISS.SI-ID 3235963]

REDENŠEK, Sara, JENKO BIZJAN, Barbara, TROŠT, Maja, DOLŽAN, Vita. Clinical-pharmacogenetic predictive models for time to occurrence of levodopa related motor complications in Parkinson's disease. Frontiers in genetics, 2019, vol. 10, 1-12, doi: 10.3389/fgene.2019.00461. [COBISS.SI-ID 34312153]

ŠMIGOC SCHWEIGER, Darja, GORIČAR, Katja, HOVNIK, Tinka, MENDEZ, Andrijana, BRATINA, Nataša, BRECELJ, Jernej, VIDAN-JERAS, Blanka, BATTELINO, Tadej, DOLŽAN, Vita. Dual role of PTPN22 but Not NLRP3 inflammasome polymorphisms in type 1 diabetes and celiac disease in children. Frontiers in pediatrics, 2019, vol. 7, 1-9, doi: 10.3389/fped.2019.00063. [COBISS.SI-ID 5957548]

KOBOLD, Nadja, JENKO BIZJAN, Barbara, TOMŠIČ, Matija, DOLŽAN, Vita, PRAPROTNIK, Sonja. ADORA2A polymorphisms influence methotrexate adverse events in rheumatoid arthritis. The Israel Medical Association Journal : IMAJ, 2019, vol. 21, 333-338. [COBISS.SI-ID 34393561]

FERJAN, Simona, JENSTERLE SEVER, Mojca, OBLAK, Tjaša, PRODAN ŽITNIK, Irena, MARC, Janja, GORIČAR, Katja, DOLŽAN, Vita, JANEŽ, Andrej. An impaired glucagon-like peptide-1 response is associated with prediabetes in polycystic ovary syndrome with obesity. Journal of international medical research, 2019, vol. 47, 4691-4700, doi: 10.1177/0300060519865351. [COBISS.SI-ID 4810865]

FRANKO, Alenka, GORIČAR, Katja, KOVAČ, Viljem, DODIČ-FIKFAK, Metoda, DOLŽAN, Vita. NLRP3 and CARD8 polymorphisms influence risk for asbestos-related diseases = Uticaj NLRP3 I CARD8 polimorfizama na bolesti u vezi sa azbestom. Journal of Medical Biochemistry, 2019, vol. 38, 1-10, doi: 10.2478/jomb-2019-0025. [COBISS.SI-ID 3362171]

REDENŠEK, Sara, FLISAR, Dušan, KOJOVIĆ, Maja, GREGORIČ KRAMBERGER, Milica, GEORGIEV, Dejan, PIRTOŠEK, Zvezdan, TROŠT, Maja, DOLŽAN, Vita. Genetic variability of inflammation and oxidative stress genes does not play a major role in the occurrence of adverse events of dopaminergic treatment in Parkinson's disease. Journal of neuroinflammation, 2019, vol. 16, 1-12, doi: 10.1186/s12974-019-1439-y. [COBISS.SI-ID 34211545]

KLEN, Jasna, GORIČAR, Katja, HORVAT, Simon, STOJAN, Jure, DOLŽAN, Vita. DEPTOR polymorphisms influence late complications in Type 2 diabetes patients. Pharmacogenomics, 2019, vol. 20, 879-890, doi: 10.2217/pgs-2019-0058. [COBISS.SI-ID 4283784]

ŠENK, Barbara, GORIČAR, Katja, KOVAČ, Viljem, DOLŽAN, Vita, FRANKO, Alenka. Genetic polymorphisms in aquaporin 1 as risk factors for malignant mesothelioma and biomarkers of response to cisplatin treatment. Radiology and oncology, 2019, vol. 53, 96-104, doi: 10.2478/raon-2019-0009. [COBISS.SI-ID 3171963]

LEVPUŠČEK, Kristina, GORIČAR, Katja, KOVAČ, Viljem, DOLŽAN, Vita, FRANKO, Alenka. The influence of genetic variability of DNA repair mechanisms on the risk of malignant mesothelioma. Radiology and oncology, 2019, vol. 53, 206-212, doi: 10.2478/raon-2019-0016. [COBISS.SI-ID 3171707]

HROVATIN, Karin, KUNEJ, Tanja, DOLŽAN, Vita. Genetic variability of serotonin pathway associated with schizophrenia onset, progression, and treatment. American journal of medical genetics. Part B, Neuropsychiatric genetics, 2019, vol. 180, doi: 10.1002/ajmg.b.32766. [COBISS.SI-ID 4318344]

ČLANKI / RESEARCH PAPERS 2018

JENKO, Barbara, TOMŠIČ, Matija, JEKIĆ, Biljana, MILIĆ, Vera, DOLŽAN, Vita, PRAPROTNIK, Sonja. Clinical pharmacogenetic models of treatment response to methotrexate monotherapy in Slovenian and Serbian rheumatoid arthritis patients : differences in patient's management may preclude generalization of the models. Frontiers in pharmacology, 2018, vol. 9, 1-8, doi: 10.3389/fphar.2018.00020. [COBISS.SI-ID 33649113]

ŠENK, Barbara, GORIČAR, Katja, KRAVOS, Nika Aleksandra, JENSTERLE SEVER, Mojca, JANEŽ, Andrej, DOLŽAN, Vita. SLC6A4 5HTTLPR polymorphism affects insulin secretion in patients with polycystic ovary syndrome. International Journal of Endocrinology (Online), 2018, doi: 10.1155/2018/6130487. [COBISS.SI-ID 33842649]

GUTIERREZ-CAMINO, Angela, DOLŽAN, Vita, JAZBEC, Janez, CARBONE-BAÑERES, Ana, ANDOIN, Nagore Garcia, SASTRE, Ana, ASTIGARRAGA, Itziar, NAVAJAS, Aurora, GARCIA-ORAD, Africa. Involvement of SNPs in miR-3117 and miR-3689d2 in childhood acute lymphoblastic leukemia risk. Oncotarget, 2018, vol. 9, no. 22907-22914, doi: 10.18632/oncotarget.25144. [COBISS.SI-ID 33834969]

FERDIN, Jana, GORIČAR, Katja, DOLŽAN, Vita, PLEMENITAŠ, Ana, MARTIN, Jeffrey, PETERLIN, Matija Boris, DEEKS, Steven G, LENASSI, Metka. Viral protein Nef is detected in plasma of half of HIV-infected adults with undetectable plasma HIV RNA. PloS one, 2018, vol. 13, 1-10, doi: 10.1371/journal.pone.0191613. [COBISS.SI-ID 33608665]

FRANKO, Alenka, KOTNIK, Nika, GORIČAR, Katja, KOVAČ, Viljem, DODIČ-FIKFAK, Metoda, DOLŽAN, Vita. The influence of genetic variability on the risk of developing malignant mesothelioma. Radiology and oncology, 2018, vol. 52, 105-111, doi: 10.1515/raon-2018-0004. [COBISS.SI-ID 2854779]

ŠTRBAC, Danijela, GORIČAR, Katja, DOLŽAN, Vita, KOVAČ, Viljem. Matrix metalloproteinases polymorphisms as baseline risk predictors in malignant pleural mesothelioma. Radiology and oncology, 2018, vol. 52, 160-166, doi: 10.1515/raon-2018-0005. [COBISS.SI-ID 2840955]

GASIC, Vladimir, ZUKIC, Branka, STANKOVIĆ, Biljana, JANIĆ, Dragana, DOKMANOVIC, Lidija, LAZIC, Jelena, KRSTOVSKI, Nada, DOLŽAN, Vita, JAZBEC, Janez, PAVLOVIČ, Sonja, KOTUR, Nikola. Pharmacogenomic markers of glucorticoid responses in the initial phase of remission induction therapy in childhood acute lymphoblastic leukemia. Radiology and oncology, 2018, vol. 52, 296-306, doi: 10.2478/raon-2018-0034. [COBISS.SI-ID 5314476]

LÓPEZ-RODRÍGUEZ, Rosario, FERREIRO-IGLESIAS, Aida, LIMA, Aurea, BERNARDES, Miguel, PAWLIK, Andrzej, PARADOWSKA- GORYCKA, Agnieszka, ŚWIERKOT, Jerzy, SLEZAK, Ryszard, DOLŽAN, Vita, GONZÁLEZ-ÁLVARO, Isidoro, et al. Replication study of polymorphisms associated with response to methotrexate in patients with rheumatoid arthritis. Scientific reports, 2018, vol. 8, 1-8. [COBISS.SI-ID 33834713]

MARTIN-GUERRERO, Idoia, BILBAO-ALDAITURRIAGA, Nerea, GUTIERREZ-CAMINO, Angela, SANTOS-ZORROZUA, Borja, DOLŽAN, Vita, PATIÑO-GARCIA, Ana, GARCIA-ORAD, Africa. Variants in the 14q32 miRNA cluster are associated with osteosarcoma risk in the Spanish population. Scientific reports, 2018, vol. 8, 1-8. doi: 10.1038/s41598-018-33712-4. [COBISS.SI-ID 34009817]

REDENŠEK, Sara, DOLŽAN, Vita, KUNEJ, Tanja. From genomics to omics landscapes of Parkinsonʼs disease : revealing the molecular mechanisms. Omics : a journal of integrative biology, 2018, vol. 22, 1-16, doi: 10.1089/omi.2017.0181. [COBISS.SI-ID 4035720]

ČLANKI / RESEARCH PAPERS 2017

GORIČAR, Katja, KOVAČ, Viljem, DOLŽAN, Vita. Clinical-pharmacogenetic models for personalized cancer treatment : application to malignant mesothelioma. Scientific reports, 2017, vol. 7, 1-9, doi: 10.1038/srep46537. [COBISS.SI-ID 2641275]

ESIH, Katarina, GORIČAR, Katja, DOLŽAN, Vita, RENER-PRIMEC, Zvonka. Antioxidant polymorphisms do not influence the risk of epilepsy or its drug resistance after neonatal hypoxic-ischemic brain injury. Seizure, 2017, vol. 46, 38-42, doi: 10.1016/j.seizure.2017.01.005. [COBISS.SI-ID 33101273]

WOUDEN, Cathelijne H., CAMBON-THOMSEN, Anne, CECCHIN, Erika, CHEUNG, Ka-Chun, DÁVILA-FAJARDO, Cristina Lucía, DENEER, Vera H., DOLŽAN, Vita, INGELMAN-SUNDBERG, Magnus, JÖNSSON, Siv, KARLSSON, Mats O., KLEN, Jasna, MLINŠEK, Gregor, POPLAS-SUSIČ, Tonka, et al, Ubiquitous Pharmacogenomics Consortium. Implementing pharmacogenomics in Europe : design and implementation Strategy of the Ubiquitous Pharmacogenomics Consortium. Clinical pharmacology and therapeutics, 2017, vol. 101, 341-358, doi: 10.1002/cpt.602. [COBISS.SI-ID 33082329]

REDENŠEK, Sara, TROŠT, Maja, DOLŽAN, Vita. Genetic determinants of Parkinson's disease : can they help to stratify the patients based on the underlying molecular defect?. Frontiers in aging neuroscience, 2017, vol. 9, 1-17, doi: 10.3389/fnagi.2017.00020. [COBISS.SI-ID 33093849]

HLADNIK, Anžej, FERDIN, Jana, GORIČAR, Katja, DEEKS, Steven G, PETERLIN, Matija Boris, PLEMENITAŠ, Ana, DOLŽAN, Vita, LENASSI, Metka. Trans-activation response element RNA is detectable in the plasma of a subset of aviremic HIV-1-infected patients. Acta chimica slovenica, 2017, vol. 64, 530-536, doi: 10.17344/acsi.2016.2863. [COBISS.SI-ID 33286873]

MLINŠEK, Gregor, DOLŽAN, Vita, GORIČAR, Katja, BUTUROVIĆ-PONIKVAR, Jadranka, ARNOL, Miha. The role of single nucleotide polymorphisms of CYP3A and ABCB1 on tacrolimus predose concentration in kidney transplant recipients. Clinical nephrology, 2017, vol. 88, suppl. 1, S115-S118, doi: 10.5414/CNP88FX25. [COBISS.SI-ID 3993772]

ŠTRBAC, Danijela, GORIČAR, Katja, DOLŽAN, Vita, KOVAČ, Viljem. Matrix metalloproteinases polymorphisms as prognostic biomarkers in malignant pleural mesothelioma. Disease markers, 2017, vol. 2017, 1-8, doi: 10.1155/2017/8069529. [COBISS.SI-ID 2743675]

BERTOK, Sara, DOLŽAN, Vita, GORIČAR, Katja, TREBUŠAK PODKRAJŠEK, Katarina, BATTELINO, Tadej, RENER-PRIMEC, Zvonka. The association of SCN1A p.Thr1067Ala polymorphism with epilepsy risk and the response to antiepileptic drugs in Slovenian children and adolescents with epilepsy. Seizure, 2017, vol. 51, 9-13, doi: 10.1016/j.seizure.2017.07.007. [COBISS.SI-ID 33339353]

JENKO, Barbara, LUSA, Lara, TOMŠIČ, Matija, PRAPROTNIK, Sonja, DOLŽAN, Vita. Clinical-pharmacogenetic predictive models for MTX discontinuation due to adverse events in rheumatoid arthritis. Pharmacogenomics journal, 2017, vol. 17, iss. 5, 412-418, doi: 10.1038/tpj.2016.36. [COBISS.SI-ID 32687833]

ZAJC AVRAMOVIČ, Mojca, DOLŽAN, Vita, TOPLAK, Nataša, ACCETTO, Meta, LUSA, Lara, AVČIN, Tadej. Relationship between polymorphisms in methotrexate pathway genes and outcome of methotrexate treatment in a cohort of 119 patients with juvenile idiopathic arthritis. The journal of rheumatology, 2017, vol. 44, iss. 8, 1216-1223, doi: 10.3899/jrheum.160950. [COBISS.SI-ID 4404396]

FAGANEL, Barbara, JAZBEC, Janez, BOHANEC GRABAR, Petra, RODRIGUEZ-ANTONA, Christina, DOLŽAN, Vita. Association between SLC19A1 gene polymorphism and high dose methotrexate toxicity in childhood acute lymphoblastic leukaemia and non Hodgkin malignant lymphoma : introducing a haplotype based approach. Radiology and oncology, 2017, vol. 51, 455-462, doi: 10.1515/raon-2017-0040. [COBISS.SI-ID 4563628]

Arhiv člankov / Archive



DOKTORSKE NALOGE / PhD THESES

2019

REDENŠEK, Sara. Farmakogenetski označevalci neželenih učinkov dopaminergičnega zdravljenja pri Parkinsonovi bolezni / Pharmacogenetic markers of adverse events of dopaminergic treatment in Parkonson's disease. Mentor: Vita Dolžan, somentor / comentor: Maja Trošt. [COBISS.SI-ID 302939136]

ŠTRBAC, Danijela. Vpliv izbranih polimorfizmov matriksnih metaloproteinaz na odgovor na zdravljenje in potek bolezni pri bolnikih z malignim mezoteliomom / The influence of selected polymorphisms in matrix metalloproteinases on response to treatment and disease progression in patients with mesothelioma. Mentor: Viljem Kovač; somentor / comentor: Vita Dolžan. [COBISS.SI-ID 300870144]

2018

ZAJC AVRAMOVIČ, Mojca. Genetski dejavniki učinkovitosti in varnosti zdravljenja juvenilnega idiopatskega artritisa z metotreksatom in zaviralci tumor nekrotizirajočega faktorja alfa / Genetic determinants of juvenile idiopathic arthritis treatment with methotrexate and tumor necrosis factor alpha blockers. Mentor: Tadej Avčin, somentor / comentor: Vita Dolžan. [COBISS.SI-ID 3914516]

2017

TURČIN, Arijana. Vpliv polimorfizmov gena za adenozinske receptorje (ADORA) na simptomatiko shizofrenije in pojavnost ekstrapiramidnih neželenih učinkov antipsihotičnih zdravil. Mentor: Blanka Kores Plesničar, somentor / comentor: Vita Dolžan. [COBISS.SI-ID 288920064]

MAGISTRSKE, DIPLOMSKE IN RAZISKOVALNE NALOGE / STUDENT THESES

2019

JERIHA, Jakob. Farmakogenetika lajšanja pooperativne bolečine s tramadolom / Pharmacogenetics of postoperative pain management with tramadol. Mentor: Vita Dolžan. [COBISS.SI-ID 5195855]

DRNOVŠEK, Eva: Genetska variabilnost receptorjev za holecistokinin in presnovne značilnosti ter vedenjski vzorci prehranjevanja pri bolnicah s sindromom policističnih ovarijev. Mentor: Mojca Jensterle, somentor / comentor: Vita Dolžan. Prešernovo priznanje Medicinske fakultete 2019.

PIBER, Petra, VAVPETIČ, Neža: Genetska variabilnost mehanizmov uravnavanja izražanja IL1B in tveganje za nastanek bolezni plevre, povezanih z izpostavljenostjo azbestu. Mentor: Alenka Franko, somentor / comentor: Katja Goričar. Prešernovo priznanje Medicinske fakultete 2019.

2018

HERMAN, Rok. Vpliv genetske variabilnosti v signalnih poteh oksidativnega stresa na metabolične značilnosti bolnic s sindromom policističnih ovarijev in na njihov odgovor na zdravljenje. 2018. Mentor: Vita Dolžan, somentor / comentor: Mojca Jensterle. [COBISS.SI-ID 5198508]. Prešernovo priznanje Medicinske fakultete 2018.

KUKEC, Eva. Vpliv polimorfizmov HIF1A na tveganje za nastanek epilepsije ter cerebralne paralize po neonatalni hipoksično-ishemični možganski okvari. 2018. Mentor: Zvonka Rener-Primec. [COBISS.SI-ID 3943700]. Prešernovo priznanje Medicinske fakultete 2018.

LEVPUŠČEK, Kristina. Genetska variabilnost mehanizmov popravljanja DNA in tveganja za nastanek malignega mezotelioma. Mentor: Alenka Franko. [COBISS.SI-ID 5525676]. Prešernova nagrada Medicinske fakultete 2018.

HROVATIN, Karin. Genetska variabilnost v uravnavanju genov serotoninske poti pri bolnikih s shizofrenijo. 2018. Mentor: Tanja Kunej, somentor / comentor: Vita Dolžan. [COBISS.SI-ID 9006713]

2017

MESARIČ, Vita Andreja. Vpliv genetske variabilnosti v inkretinslem sistemu na metabolične značilnosti bolnic s sindromom policističnih ovarijev in na njihov odgovor na zdravljenje z inhibitorjem dipeptidil peptidaze 4. 2017. Mentor: Vita Dolžan, somentor / comentor: Mojca Jensterle. [COBISS.SI-ID 4201644]. Prešernova nagrada Medicinske fakultete 2017.

Arhiv / Archive

2006 - Univerza v Ljubljani, Medicinska fakulteta, Institut za biokemijo.