Research - Laboratory for translational molecular endocrinology

Institute of Biochemistry
Faculty of Medicine
University of Ljubljana

Vrazov trg 2
SI 1000, Ljubljana
Slovenia

Tel: +386-1-543-7672
Fax: +386-1-543-7641


Laboratory for translational molecular endocrinology
RESEARCH I MEMBERS I FUNDING I THESES I AWARDS I PUBLICATIONS I COLLABORATIONS I EQUIPMENT I NEWS

	THESES PhD THESES JANŠA Vid. Identification and analysis of new protein markers for endometriosis: doctoral thesis. 2023. [COBISS.SI-ID 184917763] ROŠKAR Luka. Study of angiogenesis-related proteins and mRNA expression in plasma and tissue of endometrial cancer patients. 2023. [COBISS.SI-ID 170348291] HOJNIK Marko. Enzymes aldo-keto reductases and estrogen receptors as potential predictive markers of endometrial cancer and ovarian cancer. 2023. [COBISS.SI-ID 159972099] PAVLIČ Renata. Local estrogen biosynthesis and the roles of SLC and ABC gene families of transporter proteins in endometrial and ovarian cancers. 2022. [COBISS.SI-ID 135486467] KNIFIC Tamara. Identification of novel biomarkers for endometriosis and endometrial cancer using proteomic and metabolomic approaches. 2018. [COBISS.SI-ID 33878489] SINREIH Maša. Studies of progesterone metabolism and the roles of metabolites in endometrial cancer and endometriosis. 2015. [COBISS.SI-ID 279853824] KOCBEK Vida. Study of potential biomarkers in ovarian endometriosis. 2013. [COBISS.SI-ID 782967] BERANIČ Nataša. Study of progesterone metabolism, role of aldo-keto reductases and progestins in endometriosis. 2013. [COBISS.SI-ID 266472448] HEVIR Neli. Studies on estrogen and progesterone metabolism in endometrial cancer and ovarian endometriosis. 2011. [COBISS.SI-ID 258770688] BRUNSKOLE ŠVEGELJ Mojca. Structure/function relationship of short-chain dehydrogenases/reductases and their inhibitors. 2011 (supervisor Prof. Dr. Jure Stojan). [COBISS.SI-ID 256628736] STARČEVIČ Štefan. Design, synthesis and evaluation of new nonsteroidal inhibitors of 17ß-hydroxysteroid dehydrogenase type 1. 2011 (supervisor Prof. Dr. Stanislav Gobec). [COBISS.SI-ID 3030385] BROŽIČ Petra. Preparation of recombinant human hydroxysteroid dehydrogenases and study of their inhibitors. 2010. [COBISS.SI-ID 251130880] ŠMUC Tina. Regulation of estrogen and progesterone action in endometriosis and endometrial cancer. 2009. [COBISS.SI-ID 244659200] KRISTAN Katja. Structure/function relationship in fungal 17beta-hydroxysteroid dehydrogenase, a model enzyme of the short-chain dehydrogenase/reductase superfamily. 2005. [COBISS.SI-ID 2848020] MSc THESES KREFT Tinkara. Study on the influence of estrogens on the unresponsiveness of an ovarian cancer cell line to carboplatin. 2023. [COBISS.SI-ID 174362115] ŠTURM Lea. A study of androgen synthesis in endometrial cancer model cell lines. 2023. [COBISS.SI-ID 151363843] GJORGOSKA Marija. Synthesis of estrogens in cell lines of endometrial and ovarian cancer. 2021. [COBISS.SI-ID 55705859] KRISTAN Katja. Significance of individual amino acid residues for activity of 17beta-hydroxysteroid dehydrogenase from fungus Cochliobolus lunatus - preparation and characterization of mutant proteins. 2003. [COBISS.SI-ID 2621972] BSc THESES ŽUMER Alenka. Analysis of certain possible reaction mechanisms of 17[beta]-hydroxysteroid dehydrogenase from filamentous fungus Cochliobolus lunatus. 2014. [COBISS.SI-ID 4369528] ŠKET Aleš. Detection of proteins AKR1B1 and AKR1B10 in endometrial cancer. 2013. [COBISS.SI-ID 30586073] SVOLJŠAK Katja. Determination of presence of estrogen quinone detoxification enzymes in endometrial cancer. 2013. [COBISS.SI-ID 3446897] ČESEN Marjeta. Derivatives of 2-phenylcinnamic acid as inhibitors of human hydroxysteroid dehydrogenases AKR1C1 and AKR1C3. 2011. [COBISS.SI-ID 3088497] SINREIH Maša. New derivatives of antranilic acid as inhibitors of aldo/keto-reductases AKR1C1-AKR1C3. 2011. [COBISS.SI-ID 3054449] BOŽNAR Polona. Implementation of Suzuki cross coupling reaction for preparation of indole and coumarin derivatives as potential inhibitors of 17ß-hydroksysteroid dehydrogenase type 1. 2011. [COBISS.SI-ID 2997105] BERČIČ Nejc. Synthesis of coumarin derivatives as potencial inhibitors of 17ß-hydroxysteroid dehydrogenase type 1. 2011. [COBISS.SI-ID 2998129] MEDAR Maja. Evaluation of CYP1B1 and COMT protein levels in endometrial cancer. 2010. [COBISS.SI-ID 2815089] BARLE Nina. Expression of estrogen receptor alpha and polymorphisms of estrogen ESR 1 in endometrial cancer. 2008. [COBISS.SI-ID 2356593] KERBLER Vanja. Flavonoids as inhibitors of recombinant trihydroxynaphthalene reductase from fungus Curvularia lunata. 2008. [COBISS.SI-ID 2434673] KRAJNIK Mateja. Derivatives of cyclopentane and flavonoids as inhibitors of human hydroxysteroid dehydrogenase AKR1C3. 2008. [COBISS.SI-ID 2353265] LOZIČ Eva. Expression studies of estrogen and progesterone receptors in endometrial cancer. 2008. [COBISS.SI-ID 1848911] GOSTIČ Katja. Detection of protein AKR1C3 in ovarian cyst samples from female patients with ovarian endometriosis. 2007. [COBISS.SI-ID 2163825] BAJC Gregor. Expression studies of 17[beta]-hydroxysteroid-dehydrogenase AKR1C3 in endometrial cancer. 2007. [COBISS.SI-ID 1737039] ABRAHAMSBERG Jana. Derivatives of anthranilic acid as inhibitors of human hydroxysteroid dehydrogenase AKR1C1. 2007. [COBISS.SI-ID 2141553] BEVK Alenka. Derivatives of cyclopentane, phthalimidie and pyriidine as inhibitors of human hydroxysteroid dehydrogenase AKR1C1. 2007. [COBISS.SI-ID 2106225] ZORKO Karmen. Synthesis of nonphysiological substrate and searching for inhibitors of fungal trihydroxynaphthalene reductase. 2007. [COBISS.SI-ID 2143857] GOMBOC Nataša. Derivatives of cinnamic acid as inhibitors of human hydroxysteroid dehydrogenases AKR1C1 and AKR1C3. 2006. [COBISS.SI-ID 1944433] GOLOB Barbara. Naphthalene derivatives as inhibitors of human hydroxysteroid dehydrogenases AKR1C1 and AKR1C3. 2006. [COBISS.SI-ID 1980785] BRUNSKOLE Mojca. Searching for inhibitors of trihydroxynaphthalene reductase from fungus Curvularia lunata as potential antimicotic drugs. 2006. [COBISS.SI-ID 1904753] STARČEVIĆ Štefan. New cinnamic acid derivatives as inhibitors of 17ß-hydroxysteroid dehidrogenases. 2006. [COBISS.SI-ID 1888625] KOVAČIČ Petra Brina. Significance of individual amino acid residues for substrate and coenzyme specificity of 17beta-hydroxysteroid dehydrogenase from the fungus Cochliobolus lunatus. 2006. [COBISS.SI-ID 1618767] BROŽIČ Petra. Searching for inhibitors of recombinant human hydroxysteroid-dehidrigenase AKR1C3. 2005. [COBISS.SI-ID 1698161] FURMAN Tjaša. Hepapeptide phage display library as a tool for searching potential peptide inhibitors of recombinant 17ß-hydroxysteroid-dehydrogenase from the fungus Cochliobolus lunatus. 2005. [COBISS.SI-ID 1842033] BRADAČ Mateja. Phytoestrogens and cinnamic acid derivatives as inhibitors of recombinant human hydroxysteroid dehydrogenases AKR1C1 in AKR1C3. 2005. [COBISS.SI-ID 1731953] BRAČUN Jure. Synthesis of derivatives of antranilic acid as potential ihibitors of human hydroxysteroid dehydrogenase AKR1C1. 2005. [COBISS.SI-ID 1703281] ŠMUC Tina. Isolation and characterization of recombinant human hydroxysteroid dehydrogenase AKR1C3 and studies of AKR1C3 gene expression in endometrial cancer. 2004. [COBISS.SI-ID 26156293] LAPORNIK Ajda. Preparation of recombinant human 20a-hydroxysteroid dehydrogenase (AKR1C1) and studies of AKR1C1 gene expression in endometrial cancer. 2004. [COBISS.SI-ID 1596017] KRAJNC Katja. Phytoestrogens and cinnamic acid derivatives as inhibitors of recombinant 17[beta]-hydroxysteroid-dehydrogenase from the fungus Cochliobolus lunatus. 2004. [COBISS.SI-ID 1460337] SOVA Matej. Synthesis and evaluation of cinnamic acid esters as inhibitors of recombinant 17ß-hydroksysteroid dehydrogenase from the fungus Cochliobolus lunatus. 2004. [COBISS.SI-ID 1499761] MAČEK Melita Ana. Isolation and physiochemical characterization of recombinant 17[beta]-hydroxysteroid dehydrogenase (from the fungus Cochliobolus lunatus). 2002. [COBISS.SI-ID 2630008]