Institute of Biochemistry
Faculty of Medicine
University of Ljubljana

Vrazov trg 2
SI 1000, Ljubljana
Slovenia

Tel: +386-1-543-7672
Fax: +386-1-543-7641


 



 

Laboratory for molecular basis of hormone-dependent diseases and biomarkers (0381-059)

RESEARCH  I  MEMBERS  I  FUNDING  I  THESES  I  AWARDS  I  PUBLICATIONS  I  COLLABORATIONS  I  EQUIPMENT
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Katja KristanMEMBERS


Katja Kristan

SENIOR SCIENTIST (part time)

E-mail: katja.kristan@mf.uni-lj.si


EDUCATION:

PhD in Biochemistry and Molecular Biology (Faculty of Medicine, University of Ljubljana, Slovenia, 2005)
MSc in Biochemistry and Molecular Biology (Faculty of Medicine, University of Ljubljana, Slovenia, 2003)
MPharm (Faculty of Pharmacy, University of Ljubljana, Slovenia, 2001)


PROFESSIONAL EXPERIENCE

Reasearch Fellow, Faculty of Medicine, University of Ljubljana, Slovenia (2017–present)
Assistant Professor of Biochemistry, Faculty of Medicine, University of Ljubljana, Slovenia (2012–2017)
Visiting Researcher, Novartis Institutes for BioMedical Research (NIBR), Cambridge, MA, USA; (March–April 2010)
Postdoctoral Researcher, Helmholtz Zentrum München, German Research Center for Environmental Health, Institute for Experimental Genetics, Neuherberg, Germany (2008, 10 months)
Visiting Researcher, Novartis Institutes for BioMedical Research (NIBR), Cambridge, MA, USA; (February 2008)
Visiting Researcher, Laboratory of Bacterial Envelopes and Antibiotics, University Paris-Sud, Orsay, France (February 2007)
Visiting Researcher, Conway Institute, University College Dublin, Ireland (October 2006)
Visiting Researcher, Laboratory of Bacterial Envelopes and Antibiotics, University Paris-Sud, Orsay, France (March–April 2006)
Teaching Assistant, Faculty of Medicine, University of Ljubljana, Slovenia (2006-2012)
Visiting Scholar, Helmholtz Zentrum München, German Research Center for Environmental Health, Institute for Experimental Genetics, Neuherberg, Germany (November–December 2005)
PhD student, Helmholtz Zentrum München, German Research Center for Environmental Health, Institute for Experimental Genetics, Neuherberg, Germany (October 2002–April 2003, August 2003–October 2003, November–December 2004)


FELLOWSHIPS AND AWARDS

Lek Award “Prima rešitev 2012” (2013)
The Jožef Stefan Golden Emblem Prize Award for research accomplishments (2007)
Futurum Award for PhD research accomplishments (2006)
Krka Prize for PhD research accomplishments (2005)
WFS (World Federation of Scientists) Grant (2004–2005)
Krka Prize for MSc research accomplishments (2003)
FEBS Short-term Fellowship (2003)
DAAD Fellowship (2002-2003)
Zois Post-gradute Fellowship (2001–2003)


RESEARCH INTERESTS

Enzyme activity and inhibition
Models for predicting drug permeability


SELECTED PUBLICATIONS

CASSETTA Alberto, STOJAN Jure, KRASTANOVA Ivet, KRISTAN Katja, BRUNSKOLE ŠVEGELJ Mojca, LAMBA Doriano, LANIŠNIK RIŽNER Tea. Structural basis for inhibition of 17β-hydroxysteroid dehydrogenases by phytoestrogens: The case of fungal 17β-HSDcl. The Journal of Steroid Biochemistry and Molecular Biology, 2017, 171: 80-93, doi: 10.1016/j.jsbmb.2017.02.020. [COBISS.SI-ID 33183449]

PETRUŠEVSKA Marija, HORVAT Matej, PETERNEL Luka, KRISTAN Katja. High-throughput automated dissolution method applicable for a wide dose range of controlled release pellets. Drug Development and Industrial Pharmacy, 2016, 42 (7): 1149-1157, doi: 10.3109/03639045.2015.1117485. [COBISS.SI-ID 1595996

ERDANI-KREFT Mateja, DRAGIN JERMAN Urška, LASIČ Eva, HEVIR-KENE Neli, LANIŠNIK RIŽNER Tea, PETERNEL Luka, KRISTAN Katja. The characterization of the human cell line Calu-3 under different culture conditions and its use as an optimized in vitro model to investigate bronchial epithelial function. European Journal of Pharmaceutical Sciences, 2015, 69: 1-9, doi: 10.1016/j.ejps.2014.12.017. [COBISS.SI-ID 1574236]

ERDANI-KREFT Mateja, DRAGIN JERMAN Urška, LASIČ Eva, LANIŠNIK RIŽNER Tea, HEVIR-KENE Neli, PETERNEL Luka, KRISTAN Katja. The characterization of the human nasal epithelial cell line RPMI 2650 under different culture conditions and their optimization for an appropriate in vitro nasal model. Pharmaceutical Research, 2015, Vol. 32, 665-679, doi: 10.1007/S11095-014-1494-0. [COBISS.SI-ID 1567580]

PETERNEL Luka, KRISTAN Katja, PETRUŠEVSKA Marija, LANIŠNIK RIŽNER Tea, LEGEN Igor. Suitability of isolated rat jejunum model for demonstration for BCS-based biowaiver request. Journal of Pharmaceutical Sciences, 2012, Vol. 101, 1436-1449, doi: 10.1002/jps.23027. [COBISS.SI-ID 1477468]

KRISTAN Katja, LANIŠNIK RIŽNER Tea. Steroid-transforming enzymes in fungi. Journal of Steroid Biochemistry and Molecular Biology, 2012, Vol. 129, 79-91, doi: 10.1016/j.jsbmb.2011.08.012. [COBISS.SI-ID 28853465]

Author's publication in PubMed.


TEACHING AND MENTHORSHIP

Undergraduate courses (Faculty of Medicine, University of Ljubljana, Slovenia)

Biochemistry (laboratory practical classes)


Supervision

Mojca BRUNSKOLE and Štefan STARČEVIĆ: New cinnammic acid derivatives as inhibitors of 17β-hydroxysteroid dehydrogenase. 35th Krka Prizes (Undergraduate research work) Novo mesto: Krka, 2005. [COBISS.SI-ID 1824881]

JARC Tina. Determination of reference permeability coefficients for the biopharmaceutical classification system of active substances on Caco-2 cell model (Undergraduate theses) Ljubljana: [T. Jarc], 2013. [COBISS.SI-ID 3531377]

ČUČEK Evelin. Development of a high-throughput automated dissolution method on automated pipettor (Undergraduate theses) Ljubljana: [E. Čuček], 2014. [COBISS.SI-ID 3624305]